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On the statistical significance of nucleic acid similarities.

When evaluating sequence similarities among nucleic acids by the usual methods, statistical significance is often found when the biological significance of the similarity is dubious. We demonstrate that the known statistical properties of nucleic acid sequences strongly affect the statistical distri...

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Bibliographic Details
Main Authors: Lipman, D J, Wilbur, W J, Smith, T F, Waterman, M S
Format: Artigo
Language:Inglês
Published: 1984
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC320998/
https://ncbi.nlm.nih.gov/pubmed/6694902
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