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De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

The bacterial pathogen Legionella pneumophila exploits host cell vesicle transport by transiently manipulating the activity of the small guanosine triphosphatase (GTPase) Rab1. The effector protein SidM recruits Rab1 to the Legionella-containing vacuole (LCV), where it activates Rab1 and then AMPyla...

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Autors principals: Neunuebel, M. Ramona, Chen, Yang, Gaspar, Andrew H., Backlund, Peter S., Yergey, Alfred, Machner, Matthias P.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209958/
https://ncbi.nlm.nih.gov/pubmed/21680813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1207193
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