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A Sequence-Specific Threading Tetraintercalator with an Extremely Slow Dissociation Rate Constant

A long-lived and sequence specific ligand-DNA complex would make possible the modulation of biological processes for extended periods. We have been investigating the threading polyintercalation approach to DNA recognition in which chains of aromatic units thread back and forth repeatedly through the...

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Hlavní autoři: Holman, Garen G., Zewail-Foote, Maha, Smith, Amy Rhoden, Johnson, Kenneth A., Iverson, Brent L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209807/
https://ncbi.nlm.nih.gov/pubmed/22024884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1151
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