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Regulating complement in the kidney: insights from CFHR5 nephropathy

Complement factor H related protein 5 (CFHR5) nephropathy is a monogenic disorder of complement regulation that is endemic in Cyprus. The disease is characterised by haematuria, C3 glomerulonephritis and kidney failure. Its identification suggests a role for the CFHR5 protein in the regulation of co...

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Bibliografiske detaljer
Main Authors: Gale, Daniel P., Pickering, Matthew C.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Limited 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209641/
https://ncbi.nlm.nih.gov/pubmed/22065842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008052
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