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Modulation of AP-endonuclease1 levels associated with hepatic cirrhosis in rat model treated with human umbilical cord blood mononuclear stem cells

Oxidative stress in liver cells may contribute to the etiology of hepatic diseases, as in liver cirrhosis. AP-Endonuclease1 (APE1/Ref-1) is essential for cell protection toward oxidative stress by acting as a transcriptional regulator of pro-survival genes and as a redox sensitive protein. The aim o...

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Hlavní autoři: Bassiouny, Ahmad R, Zaky, Amira Z, Abdulmalek, Shaymaa A, Kandeel, Kamal M, Ismail, Alaa, Moftah, Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209610/
https://ncbi.nlm.nih.gov/pubmed/22076170
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