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Celecoxib or naproxen treatment does not benefit depressive symptoms in persons aged 70 and over: findings from a randomized controlled trial

BACKGROUND: Several lines of evidence suggest that inflammatory mechanisms may be involved in the severity and progression of depression. One pathway implicated is the production of prostaglandins via the enzyme cyclooxygenase (COX). Although late life depression in particular has been associated wi...

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Autors principals: Fields, Cynthia, Drye, Lea, Vaidya, Vijay, Lyketsos, Constantine
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209494/
https://ncbi.nlm.nih.gov/pubmed/21775876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JGP.0b013e318227f4da
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