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Derivation of haploid embryonic stem cells from mouse embryos

Most animals are diploid but haploid-only and male-haplo species have been described (1). Diploid genomes of complex organisms limit genetic approaches in biomedical model species such as in mice. To overcome this problem experimental induction of haploidy has been used in fish (2,3). In contrast, h...

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Bibliografiska uppgifter
Huvudupphovsmän: Leeb, Martin, Wutz, Anton
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209452/
https://ncbi.nlm.nih.gov/pubmed/21900896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10448
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