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An analysis of cosmid clones of nuclear DNA from Trypanosoma brucei shows that the genes for variant surface glycoproteins are clustered in the genome.

Trypanosoma brucei contains more than a hundred genes coding for the different variant surface glycoproteins (VSGs). Activation of some of these genes involves the duplication of the gene (the basic copy or BC) and transposition of the duplicate to an expression site (yielding the expression-linked...

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Udgivet i:Nucleic Acids Res
Principais autores: Van der Ploeg, L H, Valerio, D, De Lange, T, Bernards, A, Borst, P, Grosveld, F G
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6292859/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/10.19.5905
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