The SI Strain of Measles Virus Derived from a Patient with Subacute Sclerosing Panencephalitis Possesses Typical Genome Alterations and Unique Amino Acid Changes That Modulate Receptor Specificity and Reduce Membrane Fusion Activity

Subacute sclerosing panencephalitis (SSPE) is a fatal sequela associated with measles and is caused by persistent infection of the brain with measles virus (MV). The SI strain was isolated in 1976 from a patient with SSPE and shows neurovirulence in animals. Genome nucleotide sequence analyses showe...

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Detalhes bibliográficos
Main Authors: Seki, Fumio, Yamada, Kentaro, Nakatsu, Yuichiro, Okamura, Koji, Yanagi, Yusuke, Nakayama, Tetsuo, Komase, Katsuhiro, Takeda, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209319/
https://ncbi.nlm.nih.gov/pubmed/21917959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05067-11
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