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Host-Soluble Galectin-1 Promotes HIV-1 Replication through a Direct Interaction with Glycans of Viral gp120 and Host CD4

Sexual transmission of HIV-1 requires virus adsorption to a target cell, typically a CD4(+) T lymphocyte residing in the lamina propria, beneath the epithelium. To escape the mucosal clearance system and reach its target cells, HIV-1 has evolved strategies to circumvent deleterious host factors. Gal...

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Detalhes bibliográficos
Main Authors: St-Pierre, Christian, Manya, Hiroshi, Ouellet, Michel, Clark, Gary F., Endo, Tamao, Tremblay, Michel J., Sato, Sachiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209312/
https://ncbi.nlm.nih.gov/pubmed/21880749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05351-11
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