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A Mutation in U(L)15 of Herpes Simplex Virus 1 That Reduces Packaging of Cleaved Genomes

Herpesvirus genomic DNA is cleaved from concatemers that accumulate in infected cell nuclei. Genomic DNA is inserted into preassembled capsids through a unique portal vertex. Extensive analyses of viral mutants have indicated that intact capsids, the portal vertex, and all components of a tripartite...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Kui, Wills, Elizabeth G., Baines, Joel D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209300/
https://ncbi.nlm.nih.gov/pubmed/21880766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00857-11
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