The Interferon-Inducible Gene viperin Restricts West Nile Virus Pathogenesis

Type I interferon (IFN) signaling coordinates an early antiviral program in infected and uninfected cells by inducing IFN-stimulated genes (ISGs) that modulate viral entry, replication, and assembly. However, the specific antiviral functions in vivo of most ISGs remain unknown. Here, we examined the...

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Bibliographic Details
Main Authors: Szretter, Kristy J., Brien, James D., Thackray, Larissa B., Virgin, Herbert W., Cresswell, Peter, Diamond, Michael S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209274/
https://ncbi.nlm.nih.gov/pubmed/21880757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05519-11
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