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The RNA Polymerase Omega Factor RpoZ Is Regulated by PhoP and Has an Important Role in Antibiotic Biosynthesis and Morphological Differentiation in Streptomyces coelicolor

The RNA polymerase (RNAP) omega factor (ω) forms a complex with the α(2)ββ′ core of this enzyme in bacteria. We have characterized the rpoZ gene of Streptomyces coelicolor, which encodes a small protein (90 amino acids) identified as the omega factor. Deletion of the rpoZ gene resulted in strains wi...

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Autors principals: Santos-Beneit, Fernando, Barriuso-Iglesias, Mónica, Fernández-Martínez, Lorena T., Martínez-Castro, Miriam, Sola-Landa, Alberto, Rodríguez-García, Antonio, Martín, Juan F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209170/
https://ncbi.nlm.nih.gov/pubmed/21908625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00465-11
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