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Characterization of a Feedback-Resistant Mevalonate Kinase from the Archaeon Methanosarcina mazei

The mevalonate pathway is utilized for the biosynthesis of isoprenoids in many bacterial, eukaryotic, and archaeal organisms. Based on previous reports of its feedback inhibition, mevalonate kinase (MVK) may play an important regulatory role in the biosynthesis of mevalonate pathway-derived compound...

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Detalhes bibliográficos
Main Authors: Primak, Yuliya A., Du, Mai, Miller, Michael C., Wells, Derek H., Nielsen, Alex T., Weyler, Walter, Beck, Zachary Q.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209144/
https://ncbi.nlm.nih.gov/pubmed/21908638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.05761-11
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