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Characterization of a Feedback-Resistant Mevalonate Kinase from the Archaeon Methanosarcina mazei

The mevalonate pathway is utilized for the biosynthesis of isoprenoids in many bacterial, eukaryotic, and archaeal organisms. Based on previous reports of its feedback inhibition, mevalonate kinase (MVK) may play an important regulatory role in the biosynthesis of mevalonate pathway-derived compound...

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Autori principali: Primak, Yuliya A., Du, Mai, Miller, Michael C., Wells, Derek H., Nielsen, Alex T., Weyler, Walter, Beck, Zachary Q.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209144/
https://ncbi.nlm.nih.gov/pubmed/21908638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.05761-11
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