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Characterization of a Feedback-Resistant Mevalonate Kinase from the Archaeon Methanosarcina mazei

The mevalonate pathway is utilized for the biosynthesis of isoprenoids in many bacterial, eukaryotic, and archaeal organisms. Based on previous reports of its feedback inhibition, mevalonate kinase (MVK) may play an important regulatory role in the biosynthesis of mevalonate pathway-derived compound...

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Bibliographische Detailangaben
Hauptverfasser: Primak, Yuliya A., Du, Mai, Miller, Michael C., Wells, Derek H., Nielsen, Alex T., Weyler, Walter, Beck, Zachary Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209144/
https://ncbi.nlm.nih.gov/pubmed/21908638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.05761-11
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