Molecular Bacterial Load Assay, a Culture-Free Biomarker for Rapid and Accurate Quantification of Sputum Mycobacterium tuberculosis Bacillary Load during Treatment

A molecular assay to quantify Mycobacterium tuberculosis is described. In vitro, 98% (n = 96) of sputum samples with a known number of bacilli (10(7) to 10(2) bacilli) could be enumerated within 0.5 log(10). In comparison to culture, the molecular bacterial load (MBL) assay is unaffected by other mi...

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Detalhes bibliográficos
Main Authors: Honeyborne, Isobella, McHugh, Timothy D., Phillips, Patrick P. J., Bannoo, Selina, Bateson, Anna, Carroll, Nora, Perrin, Felicity M., Ronacher, Katharina, Wright, Laura, van Helden, Paul D., Walzl, Gerhard, Gillespie, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209113/
https://ncbi.nlm.nih.gov/pubmed/21900522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00547-11
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