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Dexamethasone-Induced Cytokine Changes Associated with Diminished Disease Severity in Horses Infected with Anaplasma phagocytophilum

Anaplasma phagocytophilum is the zoonotic cause of granulocytic anaplasmosis. We hypothesized that immune response, specifically gamma interferon (IFN-γ), plays a role in disease severity. To test this, horses were infected and IFNG expression was pharmacologically downregulated using corticosteroid...

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Detalhes bibliográficos
Main Authors: Davies, R. S., Madigan, J. E., Hodzic, E., Borjesson, D. L, Dumler, J. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209032/
https://ncbi.nlm.nih.gov/pubmed/21880854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05034-11
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