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mRNA-deficient beta o-thalassemia results from a single nucleotide deletion.

The beta-globin gene of a patient with mRNA-deficient beta o-thalassemia has been sequenced. We find a single nucleotide deletion in amino acid codon 44 that produces a UGA terminator at codon 60. We have previously shown that the beta-globin mRNA of this patient is correctly spliced and polyadenyla...

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Détails bibliographiques
Auteurs principaux: Kinniburgh, A J, Maquat, L E, Schedl, T, Rachmilewitz, E, Ross, J
Format: Artigo
Langue:Inglês
Publié: 1982
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC320886/
https://ncbi.nlm.nih.gov/pubmed/6292840
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