In Vivo Hypermutation of Xenotropic Murine Leukemia Virus-Related Virus DNA in Peripheral Blood Mononuclear Cells of Rhesus Macaque by APOBEC3 Proteins

The gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV), replicates to high titers in some human cell lines and is able to infect non-human primates. To determine whether APOBEC3 (A3) proteins restrict XMRV infections in a non-human primate model, we sequenced proviral DNA from pe...

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Bibliographic Details
Main Authors: Zhang, Ao, Bogerd, Hal, Villinger, Francois, Gupta, Jaydip Das, Dong, Beihua, Klein, Eric A., Hackett, John, Schochetman, Gerald, Cullen, Bryan R., Silverman, Robert H.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208790/
https://ncbi.nlm.nih.gov/pubmed/21982221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.08.030
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