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α-Tocopherol injections in rats up-regulates hepatic ABC-transporters, but not cytochrome P450 enzymes
The role of hepatic xenobiotic regulatory mechanisms to modulate hepatic α-tocopherol concentrations during excess vitamin E administration remains unclear. We hypothesized that increased hepatic α-tocopherol would cause a marked xenobiotic response. Thus, we assessed cytochrome P450 oxidation syste...
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Auteurs principaux: | , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208783/ https://ncbi.nlm.nih.gov/pubmed/21945367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.08.033 |
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