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α-Tocopherol injections in rats up-regulates hepatic ABC-transporters, but not cytochrome P450 enzymes

The role of hepatic xenobiotic regulatory mechanisms to modulate hepatic α-tocopherol concentrations during excess vitamin E administration remains unclear. We hypothesized that increased hepatic α-tocopherol would cause a marked xenobiotic response. Thus, we assessed cytochrome P450 oxidation syste...

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Main Authors: Traber, Maret G., Labut, Edwin M., Leonard, Scott W., Lebold, Katie M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208783/
https://ncbi.nlm.nih.gov/pubmed/21945367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.08.033
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