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West Nile virus infection does not induce PKR activation in rodent cells
dsRNA-activated protein kinase (PKR) is activated by viral dsRNAs and phosphorylates eIF2a reducing translation of host and viral mRNA. Although infection with a chimeric West Nile virus (WNV) efficiently induced PKR and eIF2a phosphorylation, infections with natural lineage 1 or 2 strains did not....
Bewaard in:
| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208726/ https://ncbi.nlm.nih.gov/pubmed/21982595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.08.008 |
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