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Tamoxifen Downregulates Ets-oncogene Family Members ETV4 and ETV5 in Benign Breast Tissue: Implications for Durable Risk Reduction

BACKGROUND: Five years of tamoxifen reduces breast cancer risk by nearly 50% but is associated with significant side-effects and toxicities. A better understanding of the direct and indirect effects of tamoxifen in benign breast tissue could elucidate new mechanisms of breast carcinogenesis, suggest...

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Detalhes bibliográficos
Main Authors: Euhus, David, Bu, Dawei, Xie, Xian-Jin, Sarode, Venetia, Ashfaq, Raheela, Hunt, Kelly, Xia, Weiya, O’Shaughnessy, Joyce, Grant, Michael, Arun, Banu, Dooley, William, Miller, Alexander, Flockhart, David, Lewis, Cheryl
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208724/
https://ncbi.nlm.nih.gov/pubmed/21778330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0186
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