Mitochondrial DNA Copy Number and Pancreatic Cancer in the Alpha-Tocopherol Beta-Carotene Cancer Prevention (ATBC) Study

BACKGROUND: Diabetes, obesity, and cigarette smoke, consistent risk factors for pancreatic cancer, are sources of oxidative stress in humans that could cause mitochondrial DNA (mtDNA) damage and increase mtDNA copy number. METHODS: To test whether higher mtDNA copy number is associated with increase...

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Autori principali: Lynch, Shannon M., Weinstein, Stephanie J., Virtamo, Jarmo, Lan, Qing, Lui, Chin-San, Cheng, Wen-Ling, Rothman, Nathaniel, Albanes, Demetrius, Stolzenberg-Solomon, Rachael Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208722/
https://ncbi.nlm.nih.gov/pubmed/21859925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0002
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