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Neuregulin Receptor ErbB4 Functions as a Transcriptional Cofactor for the Expression of Surfactant Protein B in the Fetal Lung

Sufficient pulmonary surfactant production is required for the fetal–neonatal transition, especially in preterm infants. Neuregulin (NRG) and its transmembrane receptor ErbB4 positively regulate the onset of fetal surfactant synthesis. Details of this signaling process remain to be elucidated. ErbB4...

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Detalhes bibliográficos
Main Authors: Zscheppang, Katja, Dörk, Thilo, Schmiedl, Andreas, Jones, Frank E., Dammann, Christiane E. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208619/
https://ncbi.nlm.nih.gov/pubmed/21317380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0179OC
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