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The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge

BACKGROUND AND AIM: The first genome-wide association study on birth weight was recently published and the most significant associated birth weight lowering variant was the rs900400 C-allele located near LEKR1 and CCNL1. We aimed to replicate the association with birth weight in the Danish Inter99 s...

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Detalhes bibliográficos
Main Authors: Andersson, Ehm A., Harder, Marie N., Pilgaard, Kasper, Pisinger, Charlotta, Stančáková, Alena, Kuusisto, Johanna, Grarup, Niels, Færch, Kristine, Poulsen, Pernille, Witte, Daniel R., Jørgensen, Torben, Vaag, Allan, Laakso, Markku, Pedersen, Oluf, Hansen, Torben
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208566/
https://ncbi.nlm.nih.gov/pubmed/22073261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027096
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