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Stepwise Maturation of Lytic Granules during Differentiation and Activation of Human CD8(+) T Lymphocytes
During differentiation, cytotoxic T lymphocytes (CTL) acquire their killing potential through the biogenesis and maturation of lytic granules that are secreted upon target cell recognition. How lytic granule load in lytic molecules evolves during CTL differentiation and which subsets of lytic granul...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208563/ https://ncbi.nlm.nih.gov/pubmed/22073254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027057 |
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