Metastatic Pheochromocytoma/Paraganglioma Related to Primary Tumor Development in Childhood or Adolescence: Significant Link to SDHB Mutations

PURPOSE: To present data on the high rate of SDHB mutations in patients with metastatic pheochromocytoma/paraganglioma whose initial tumor presentation began in childhood or adolescence. PATIENTS AND METHODS: From 2000 to 2010, 263 patients with pheochromocytoma/paraganglioma were evaluated through...

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Main Authors: King, Kathryn S., Prodanov, Tamara, Kantorovich, Vitaly, Fojo, Tito, Hewitt, Jacqueline K., Zacharin, Margaret, Wesley, Robert, Lodish, Maya, Raygada, Margarita, Gimenez-Roqueplo, Anne-Paule, McCormack, Shana, Eisenhofer, Graeme, Milosevic, Dragana, Kebebew, Electron, Stratakis, Constantine A., Pacak, Karel
Format: Artigo
Jezik:Inglês
Izdano: American Society of Clinical Oncology 2011
Teme:
Original Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208535/
https://ncbi.nlm.nih.gov/pubmed/21969497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.34.6353
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