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Phase I study of irinotecan and gefitinib in patients with gefitinib treatment failure for non-small cell lung cancer
BACKGROUND: Currently, no effective treatments exist for non-small cell lung cancer (NSCLC) after failure of gefitinib therapy. Pre-clinical studies have demonstrated that gefitinib-resistant NSCLC cells are more sensitive to irinotecan than parental cells, and that combined administration of irinot...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208500/ https://ncbi.nlm.nih.gov/pubmed/21915126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.375 |
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