Mammary Ductal Growth Is Impaired in Mice Lacking Leptin-Dependent Signal Transducer and Activator of Transcription 3 Signaling

Mice lacking leptin (ob/ob) or its full-length receptor (db/db) are obese and reproductively incompetent. Fertility, pregnancy, and lactation are restored, respectively, in ob/ob mice treated with leptin through mating, d 6.5 post coitum, and pregnancy. Therefore, leptin signaling is needed for lact...

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Hauptverfasser: Thorn, Stephanie R., Giesy, Sarah L., Myers, Martin G., Boisclair, Yves R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2010
Schlagworte:
Reproduction-Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208358/
https://ncbi.nlm.nih.gov/pubmed/20501669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0029
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