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Dual involvement of Caspase-4 in Inflammatory and ER Stress-induced Apoptotic Responses in Human Retinal Pigment Epithelial Cells

PURPOSE: To investigate the functional involvement of caspase-4 in human retinal pigment epithelial (hRPE) cells. METHODS: Expression and activation of caspase-4 in hRPE cells were measured after stimulation with pro-inflammatory agents IL-1β (2 ng/ml), TNF-α (20 ng/ml), lipopolysaccharide (1000 ng/...

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Detalhes bibliográficos
Main Authors: Bian, Zong-Mei, Elner, Susan G., Elner, Victor M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208232/
https://ncbi.nlm.nih.gov/pubmed/19643964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3628
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