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Mechanism of auxiliary β-subunit-mediated membrane targeting of L-type (Ca(V)1.2) channels

ABSTRACT: Ca(2+) influx via Ca(V)1/Ca(V)2 channels drives processes ranging from neurotransmission to muscle contraction. Association of a pore-forming α(1) and cytosolic β is necessary for trafficking Ca(V)1/Ca(V)2 channels to the cell surface through poorly understood mechanisms. A prevalent idea...

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Detalhes bibliográficos
Main Authors: Fang, Kun, Colecraft, Henry M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208217/
https://ncbi.nlm.nih.gov/pubmed/21746784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.214247
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