α(2)-Adrenoceptors do not mediate neuroprotection in acute ischemic stroke in mice

We assessed the neuroprotective potential of α(2)-adrenoceptors in ischemic stroke using mice with targeted deletions of individual α(2)-adrenoceptor subtypes (α(2A)(−/−), α(2B)(−/−), α(2C)(−/−), α(2A/C)(−/−)). The effects of the α(2)-adrenoceptor agonist clonidine were studied in parallel. Focal ce...

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Autors principals: Brede, Marc, Braeuninger, Stefan, Langhauser, Friederike, Hein, Lutz, Roewer, Norbert, Stoll, Guido, Kleinschnitz, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Negative Result
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208146/
https://ncbi.nlm.nih.gov/pubmed/21792243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.110
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