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Cyclooxygenase-2 Deficiency Leads to Intestinal Barrier Dysfunction and Increased Mortality During Polymicrobial Sepsis ()

Sepsis remains the leading cause of death in critically ill patients despite modern advances in critical care. Intestinal barrier dysfunction may lead to secondary bacterial translocation and the development of the multiple organ dysfunction syndrome during sepsis. Cyclooxygenase-2 (COX-2) is highly...

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Main Authors: Fredenburgh, Laura E., Velandia, Margarita M. Suarez, Ma, Jun, Olszak, Torsten, Cernadas, Manuela, Englert, Joshua A., Chung, Su Wol, Liu, Xiaoli, Begay, Cynthia, Padera, Robert F., Blumberg, Richard S., Walsh, Stephen R., Baron, Rebecca M., Perrella, Mark A.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208135/
https://ncbi.nlm.nih.gov/pubmed/21967897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101186
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