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Syntheses and Cellular Investigations of 17(3)-, 15(2)- and 13(1)-Amino Acid Derivatives of Chlorin e(6)

A series of amino acid conjugates of chlorin e(6), containing lysine or aspartic acid residues in positions 17(3), 15(2) or 13(1) of the macrocycle were synthesized and investigated as photosensitizers for photodynamic therapy of tumors. All three regioisomers were synthesized in good yields and in...

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Detalhes bibliográficos
Main Authors: Waruna Jinadasa, R. G., Hu, Xiaoke, Vicente, M. Graça H., Smith, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208129/
https://ncbi.nlm.nih.gov/pubmed/21936519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2005139
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