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Microtubules induce self-organization of polarized PAR domains in C. elegans zygotes

A hallmark of polarized cells is the segregation of the PAR polarity regulators into asymmetric domains at the cell cortex(1, 2). Antagonistic interactions involving two conserved kinases, atypical protein kinase C (aPKC) and PAR-1, have been implicated in polarity maintenance(1, 2), but the mechani...

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Detalhes bibliográficos
Main Authors: Motegi, Fumio, Zonies, Seth, Hao, Yingsong, Cuenca, Adrian A., Griffin, Erik, Seydoux, Geraldine
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208083/
https://ncbi.nlm.nih.gov/pubmed/21983565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2354
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