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Microtubules induce self-organization of polarized PAR domains in C. elegans zygotes
A hallmark of polarized cells is the segregation of the PAR polarity regulators into asymmetric domains at the cell cortex(1, 2). Antagonistic interactions involving two conserved kinases, atypical protein kinase C (aPKC) and PAR-1, have been implicated in polarity maintenance(1, 2), but the mechani...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208083/ https://ncbi.nlm.nih.gov/pubmed/21983565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2354 |
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