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Platypus TCRμ provides insight into the origins and evolution of a uniquely mammalian TCR locus()

TCRμ is an unconventional TCR that was first discovered in marsupials and appears to be absent from placental mammals and non-mammals. Here we show that TCRμ is also present in the duckbill platypus, an egg-laying monotreme, consistent with TCRμ being ancient and present in the last common ancestor...

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Détails bibliographiques
Auteurs principaux: Wang, Xinxin, Parra, Zuly E., Miller, Robert D.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208081/
https://ncbi.nlm.nih.gov/pubmed/21976776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101113
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