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Histone Deacetylases (HDAC)-Induced Histone Modifications in the Amygdala: A Role in Rapid Tolerance to the Anxiolytic Effects of Ethanol

BACKGROUND: Rapid tolerance to the anxiolytic effects of ethanol appears to be an important factor in the development of alcoholism. Here, we investigated the involvement of amygdaloid histone deacetylases (HDAC)-induced epigenetic changes in rapid ethanol tolerance (RET). METHODS: RET in rats was i...

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Détails bibliographiques
Auteurs principaux: Sakharkar, Amul J, Zhang, Huaibo, Tang, Lei, Shi, Guangbin, Pandey, Subhash C
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208078/
https://ncbi.nlm.nih.gov/pubmed/21790673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01581.x
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