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The influence of the purine 2-amino group on DNA conformation and stability. Synthesis and conformational analysis of d[T(2-aminoA)]3.

A self-complementary hexanucleotide consisting of thymidine and 2-amino-deoxyadenosine, d(TA')3, has been synthesized by a solid phase phosphotriester method. Melting studies show that the additional hydrogen bond afforded by the 2-amino group substantially stabilizes the duplex. Moreover, conf...

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Hlavní autoři: Gaffney, B L, Marky, L A, Jones, R A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1982
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC320804/
https://ncbi.nlm.nih.gov/pubmed/7122239
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