Neuroprotection from Retinal Ischemia/Reperfusion Injury by NOX2 NADPH Oxidase Deletion

PURPOSE. The aim of this study was to determine whether NOX2, one of the homologs of NADPH oxidase, plays a role in neuronal cell death during retinal ischemia. METHODS. Ischemia reperfusion (I/R) injury was generated in C57/BL6 and NOX2(−/−) mice by increasing the intraocular pressure (IOP) to 110...

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Autors principals: Yokota, Harumasa, Narayanan, Subhadra P., Zhang, Wenbo, Liu, Hua, Rojas, Modesto, Xu, Zhimin, Lemtalsi, Tahira, Nagaoka, Taiji, Yoshida, Akitoshi, Brooks, Steven E., Caldwell, Robert W., Caldwell, Ruth B.
Format: Artigo
Idioma:Inglês
Publicat: Association for Research in Vision and Ophthalmology, Inc. 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208002/
https://ncbi.nlm.nih.gov/pubmed/21917939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8318
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