HGF/c-Met related activation of β-catenin in hepatoblastoma

BACKGROUND: Activation of beta-catenin is a hallmark of hepatoblastoma (HB) and appears to play a crucial role in its pathogenesis. While aberrant accumulation of the beta-catenin is a common event in HB, mutations or deletions in CTNNB1 (beta-catenin gene) do not always account for the high frequen...

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Detalhes bibliográficos
Main Authors: Purcell, Rachel, Childs, Margaret, Maibach, Rudolf, Miles, Carina, Turner, Clinton, Zimmermann, Arthur, Sullivan, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207961/
https://ncbi.nlm.nih.gov/pubmed/21992464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-96
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