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A de novo complete BRCA1 gene deletion identified in a Spanish woman with early bilateral breast cancer
BACKGROUND: Germline mutations in either of the two tumor-suppressor genes, BRCA1 and BRCA2, account for a significant proportion of hereditary breast and ovarian cancer cases. Most of these mutations consist of deletions, insertions, nonsense mutations, and splice variants, however an increasing nu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207938/ https://ncbi.nlm.nih.gov/pubmed/21989022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-134 |
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