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Fatal Prion Disease in a Mouse Model of Genetic E200K Creutzfeldt-Jakob Disease
Genetic prion diseases are late onset fatal neurodegenerative disorders linked to pathogenic mutations in the prion protein-encoding gene, PRNP. The most prevalent of these is the substitution of Glutamate for Lysine at codon 200 (E200K), causing genetic Creutzfeldt-Jakob disease (gCJD) in several c...
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Hoofdauteurs: | , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Public Library of Science
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207931/ https://ncbi.nlm.nih.gov/pubmed/22072968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002350 |
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