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Drosophila Duplication Hotspots Are Associated with Late-Replicating Regions of the Genome

Duplications play a significant role in both extremes of the phenotypic spectrum of newly arising mutations: they can have severe deleterious effects (e.g. duplications underlie a variety of diseases) but can also be highly advantageous. The phenotypic potential of newly arisen duplications has stim...

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Detalhes bibliográficos
Main Authors: Cardoso-Moreira, Margarida, Emerson, J. J., Clark, Andrew G., Long, Manyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207856/
https://ncbi.nlm.nih.gov/pubmed/22072977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002340
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