The High-Mobility Group Box-1 Nuclear Factor Mediates Retinal Injury after Ischemia Reperfusion

PURPOSE. High-mobility group protein B1 (Hmgb1) is released from necrotic cells and induces an inflammatory response. Although Hmgb1 has been implicated in ischemia/reperfusion (IR) injury of the brain, its role in IR injury of the retina remains unclear. Here, the authors provide evidence that Hmgb...

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Main Authors: Dvoriantchikova, Galina, Hernandez, Eleut, Grant, Jeff, Santos, Andrea Rachelle C., Yang, Huan, Ivanov, Dmitry
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207720/
https://ncbi.nlm.nih.gov/pubmed/21828158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7793
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