Mitochondrial Ribosomal Protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription

Basal transcription of human mitochondrial DNA (mtDNA) in vitro requires the single-subunit, bacteriophage-related RNA polymerase, POLRMT, and transcription factor h-mtTFB2. This two-component system is activated differentially at mtDNA promoters by human mitochondrial transcription factor A (h-mtTF...

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Bibliographic Details
Main Authors: Surovtseva, Yulia V., Shutt, Timothy E., Cotney, Justin, Cimen, Huseyin, Chen, Sophia Y., Koc, Emine C., Shadel, Gerald S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207702/
https://ncbi.nlm.nih.gov/pubmed/22003127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108852108
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