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Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo
Tetherin (Bst-2 CD317) is a cell-surface protein whose expression is induced by IFNα. Although tetherin expression causes the retention of retrovirus particles on the surface of infected cells, it is not known whether tetherin inhibits retroviral replication or pathogenesis in vivo. Mutation of teth...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207693/ https://ncbi.nlm.nih.gov/pubmed/22025715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113694108 |
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