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Electron cryotomography of measles virus reveals how matrix protein coats the ribonucleocapsid within intact virions

Measles virus is a highly infectious, enveloped, pleomorphic virus. We combined electron cryotomography with subvolume averaging and immunosorbent electron microscopy to characterize the 3D ultrastructure of the virion. We show that the matrix protein forms helices coating the helical ribonucleocaps...

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Detalhes bibliográficos
Main Authors: Liljeroos, Lassi, Huiskonen, Juha T., Ora, Ari, Susi, Petri, Butcher, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207687/
https://ncbi.nlm.nih.gov/pubmed/22025713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105770108
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