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Topographic Modulation of the Orientation and Shape of Cell Nuclei and Their Influence on the Measured Elastic Modulus of Epithelial Cells

The influence of nucleus shape and orientation on the elastic modulus of epithelial cells was investigated with atomic force microscopy. The shape and orientation were controlled by presenting the epithelial cells with anisotropic parallel ridges and grooves of varying pitch at the cell substratum....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McKee, Clayton T., Raghunathan, Vijay K., Nealey, Paul F., Russell, Paul, Murphy, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207178/
https://ncbi.nlm.nih.gov/pubmed/22067151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.042
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