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DNA Multiphoton Absorption Generates Localized Damage for Studying Repair Dynamics in Live Cells

Investigations into the spatiotemporal dynamics of DNA repair using live-cell imaging are aided by the ability to generate well defined regions of ultravioletlike photolesions in an optical microscope. We demonstrate that multiphoton excitation of DNA in live cells with visible femtosecond pulses pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Daddysman, Matthew K., Fecko, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207161/
https://ncbi.nlm.nih.gov/pubmed/22067170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.031
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