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Butein, a Tetrahydroxychalcone, Suppresses Cancer-induced Osteoclastogenesis Through Inhibition of RANKL Signaling

Osteoclastogenesis is associated with aging and various age-related inflammatory chronic diseases, including cancer. Receptor activator of nuclear factor-kappaB (NF-κB) ligand (RANKL), a member of the tumor necrosis factor superfamily, has been implicated as a major mediator of bone resorption, sugg...

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Detalhes bibliográficos
Main Authors: Sung, Bokyung, Cho, Sung-Gook, Liu, Mingyao, Aggarwal, Bharat B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207026/
https://ncbi.nlm.nih.gov/pubmed/21170936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25868
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